Description

PL-SAX for Biomolecules is ideal for the anion-exchange HPLC separations of synthetic oligonucleotides. The covalently linked strong anion exchange functionality extends the operating pH and temperature range, essential for oligonucleotide purification and analysis. With PL-SAX for Biomolecules, separations using denaturing conditions of temperature, organic solvent, and high pH are all possible. PL-SAX for Biomolecules delivers improved chromatography for self-complementary or G-rich sequences that may associate to form aggregates or hairpin structures. The 5 µm material provides high-efficiency separations of n and n-1 sequences, with 8 µm, 10 µm, and 30 µm particles available for rapid scale-up. Application: For Charge Variant Analysis, Oligonucleotide Analysis, Oligos This product is only available to U.S. Domestic Customers. For research use only, not to be used in diagnostic procedures.