Description

Thorough characterization of monoclonal antibodies includes the identification and monitoring of acidic and basic isoforms. The Agilent Bio MAb HPLC columns feature a unique resin specifically designed for high-resolution, charge-based separations of monoclonal antibodies. Bio MAb columns are available in 1.7 µm, 3 µm, 5µm, and 10 µm sizes, providing higher resolution with the smaller particles. The Bio MAb column features a highly uniform, densely packed, weak cation exchange layer. This layer of the Bio MAb column is chemically bonded to the hydrophilic, polymeric coating of the Bio MAb column. Features: A packing support composed of a rigid, spherical, highly cross-linked polystyrene divinylbenzene (PS/DVB) non-porous bead Particles grafted with a hydrophilic, polymeric layer, virtually eliminating non-specific binding of antibody proteins Particles, coating and bonding are resistant to high pressures, promoting higher resolution and faster separations A highly uniform, densely packed, weak cation exchange (WCX) layer chemically bonded to the hydrophilic, polymeric coating Agilent Technologies products are intended for sale/shipment within the US only. International customers should contact their local Agilent Technologies distributor to place orders for Agilent Technologies products.